Infertility Diagnosis

Infertility Diagnosis

Infertility Diagnosis is basically a series of tests conducted by a fertility specialist to figure out the root cause of your infertility.

A person is declared infertile when a clinical pregnancy cannot be established after 12 months of regular, unprotected sexual activity or when a person's ability to reproduce is impaired. Various tests and evaluations are conducted to determine why you and your partner haven’t been able to conceive. Following infertility diagnosis, if a cause is found treatment is carried out accordingly. In a few cases, the cause of infertility is unknown. Such cases are commonly termed as unexplained infertility. Even such couples can get pregnant with infertility treatment.

The fertility diagnostic is conducted for both male and female partners since 40% of cases are reported with female infertility, 40% with male infertility,10% with both male and female factors, and the remaining 10% with unidentified causes. Patients with risk factors for infertility or female partners who are older than 35 years old may have their evaluations started earlier. 

Causes of infertility in Women

  • Failure to ovulate or ovulation disorder is the most prevalent cause of female infertility, affecting 40% of infertile women.
  • Advancing maternal age often acts as a cause of infertility because women’s ability to produce quality eggs decreases
  • If a person trying to conceive has  pelvic surgery, infection, or appendicitis it can lower the chances of getting pregnant 
  • Abnormal growth of endometrial tissue outside the uterus
  • Women who are going through early menopause i.e. before the age of 40
  • Infection, blockage, or enlargement of the fallopian tube
  • Exposure to life-threatening radiation or patients who have through chemotherapy can hinder fertility
  • Abnormalities or tumors around the cervical region
  • Illness such as thyroid, eating disorders as well as excessive physical exercise, and irregular menstruation cycle can lead to infertility

Causes of Infertility in Men

  • Exposure to harmful toxins such as lead, calcium or mercury is linked with limited production of sperm
  • Unhealthy habits such as smoking, drinking alcohol, and other substances
  • Blockage or injury in reproductive organs
  • Genetic diseases and sexually transmitted infections like chlamydia, HIV, gonorrhea, etc can affect fertility
  • People with high blood pressure and suffering from mental health issues
  • Low and abnormal production of sperm

Causes of Infertility Common in Both Men and Women

Infertility is not necessarily a female issue. Both men and women suffer from infertility issues. Women account for around one-third of all infertility, while men account for another one-third. Some common causes that affect the fertility of both men and women are:

Obesity and Underweight

Women who are underweight, overweight, or obese have no problem getting pregnant. Others, however, who may be overweight or underweight, can experience difficulties conceiving, frequently as a result of irregular periods and ovulation issues including the inability to release eggs from the ovaries. Other weight-related issues that impact the metabolic and endocrine systems can also result in infertility. These issues can arise from failing to keep an active and healthy lifestyle.

Age

The most significant factor impacting a woman's fertility is her age. The consequences of aging on a woman's fertility are still there even if being in excellent health. Every month, a woman in her mid-20s has a 25–30% chance of becoming pregnant. Early in a woman's 30s, and more so after 35, fertility often starts to decline. The likelihood of becoming pregnant by the age of 40 is about 5% for any given monthly cycle.
                                                Male fertility starts to decline around the age of 40-45. As both, the number and quality of sperm begin to deteriorate it is pretty tough to conceive. Age-related declines in male fertility are accompanied by an increase in the gestational period, risk of miscarriage, and fetal mortality.

Substance Use and Smoking

Smoking cigarettes can have an adverse effect on the health of both the mother and fetus. These include perinatal death, intrauterine growth restriction, and premature birth. In men, significant abnormalities in sperm production and erectile dysfunction can also be brought on by smoking. These include DNA damage, a decrease in sperm concentration and motility, and others.

Diagnosis and Test

A crucial step in treating infertility is determining the real cause of your inability to conceive despite having regular, unprotected sex. Your sexual history, medical history, and prior infertility treatments are the first standard inquiries. 

To diagnose male infertility, a male member must perform blood testing and semen analysis. Both examinations measure testosterone levels, sperm counts, and other male hormones. While the uterine test for infertility, ovarian reserve test, blood test, ultrasound, and hysterosalpingography are among the tests and diagnoses for female infertility.

One in ten couples reportedly have problems becoming pregnant. Therefore, the first step for such a couple is to seek assistance from fertility specialists like doctors at Nepal IVF. Doctors and specialists at Nepal IVF will evaluate your overall reproductive health by running a few tests to find any underlying fertility issues or pregnancy delays.


Some standard Fertility diagnosis tests are:

Ovulation Test

While testing ovulation a blood test is carried out to measure the hormonal level in order to determine your ovulation cycle. This will help in finding out the days when you are most fertile.

Ultrasound scan 

The uterus, tubes, and ovaries may all be structurally assessed by ultrasound. Distal fallopian tube blockage, ovarian abnormalities including ovarian cysts, and uterine abnormalities like fibroids and polyps can all be seen with ultrasound. Transvaginal ultrasound also gives your doctor the chance to gauge the proportion of eggs that are accessible. The antral follicle count is a parameter that may be related to reproductive potential.

Semen Analysis

Semen analysis at Nepal IVF examines the quantity and caliber of a man's sperm. It is one of the initial stages in identifying problems with male fertility. Semen analysis entails obtaining a semen sample and analyzing it in a lab.

Anti-Mullerian Hormone (Egg Count Test)

The anti-mullerian hormone (AMH) also termed as egg count test, which is measured by an AMH test, is related to an individual's egg count. An ovarian mass can also be identified with the use of the AMH test. Your fertility cannot be predicted even though it is related to your egg count. AMH testing is a straightforward blood test, and Nepal IVF will go over the results and any necessary next steps with you.

Ovarian Reserve Testing

Ovarian reserve testing is a simple test often carried out to measure the ovarian reserve hormone. This test indirectly estimates the amount of a woman's remaining follicular pool. A good ORT should be simple to use, repeatable, and able to distinguish between women who have a healthy ovarian response and those who don't.

Blood Test

In order to evaluate the hormone levels in the blood, blood tests are performed during the course of a woman's menstrual cycle. A woman needs healthy hormone levels for an egg to mature and the ovaries to release an egg. A typical test for women is an analysis of their follicle-stimulating hormone (FSH) levels obtained on cycle day three or three days following the start of their period. Estradiol and anti-Müllerian hormone (AMH) are two additional hormones that may be detected in blood testing.

Biopsy

A quick biopsy is conducted under anesthesia to obtain sample tissue.

Venography

Venography is conducted to check for any issues in the veins that might lead to infertility.

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