One method of artificial insemination is intrauterine insemination (IUI), which is used to treat infertility.
Sperm must travel from the vagina via the cervix, uterus, and up to the fallopian tubes during natural conception. IUI brings the sperm and egg closer together because the sperm are "washed" and concentrated before being put into the uterus.
Intrauterine insemination is intended to produce a natural pregnancy by allowing the sperm to enter the fallopian tube and fertilize an egg that is already mature. Depending on the causes of infertility, IUI can be timed to coincide with the regular cycle or with the use of fertility medications. This stage will raise the likelihood of conception in certain couples who have had problems becoming pregnant.
Who is IUI Best For?
Recommendation if IUI depends on many factors. Women with mild to severe endometriosis, difficulty with cervical mucus, semen allergies, and occasionally women carrying donor sperm are among those who frequently turn to IUI for reproductive concerns. IUI can be helpful in some circumstances, but it is not the best solution for all infertility issues. In situations of female-caused infertility, it shouldn't be done more than 5–6 times, and there is no added benefit. IVF can occasionally be recommended directly by infertility doctors.
Patients who often have the best success rates with IUI are those who:
Patients may not be eligible for IUI if they have any of the following conditions:
How is IUI Conducted?
An intrauterine insemination cycle entails taking medication to encourage the production of eggs, then using a straightforward procedure to directly inject sperm collected at the moment of ovulation into the uterus. Here are some fundamental details about the IUI process:
1. Stimulate Egg Growth
The woman begins ingesting oral or injectable medication to promote the development and expansion of her eggs. The injections are advised for a fatty area of the body, such as the stomach or the top of the thigh, and are only administered subcutaneously (under the skin). Depending on how the ovaries respond, oral medicine is often administered for 5 days whereas injectable treatment is typically used for 8–12 days.
2. Ultrasound and Blood Monitoring
While using injectable medicine, quick ultrasound checkups are necessary every 2 to 3 days to monitor the ovaries and egg production. Blood tests are also carried out to ascertain the hormone levels associated with egg development and ovarian function. Through this testing and surveillance, it is verified that everything is proceeding securely.
3. Ovulation Induced
Once a "mature" egg is present, a patient is given a "trigger injection," which causes ovulation to occur in around 36 hours. A nurse administers the injection at the clinic or by self-administration at home. Processed sperm sample: Either the male partner or a laboratory thaws and processes sperm from a donor sample. During preparation, the sperm sample is "washed" to eliminate debris, immobile sperm, and semen compounds that might cause extremely painful cramping. The sperm cells are then concentrated in a very tiny number.
4. Insemination Procedure
Similar to a standard pelvic exam, a woman is lying on a table where a tiny, long, flexible catheter is used to inject the sperm sample into the uterus. The entire process is almost painless and takes only a few seconds to complete. The chances of becoming pregnant would not be affected by getting up soon after the procedure. Occasionally, two consecutive days of insemination will be advised, but most of the time, each cycle just requires one perfectly timed insemination.
5. Follow Up
Once ovulation has occurred for a week, progesterone levels are checked. For certain individuals, extra hormone support (such as progesterone) may be advised in order to help get the uterine lining ready for conception. Progesterone support is used to women who experience recurrent miscarriages.
6. Additional Testing
Approximately two weeks after insemination, a blood test is used to determine if a pregnancy has occurred.
The advantages of undergoing IUI
IUI is considered one of the safest and easiest methods of Fertility treatment due to various reasons: Some advantages of IUI are:
For patients undergoing IUI benefits include:
Performance of IUI is influenced by a variety of factors. IUI success rates can reach as high as 20% each cycle if a couple has the process every month, depending on variables like female age, the reason for infertility, care taken in sperm washing, a medicine used for ovarian stimulation, scheduling of the IUI operation, etc. IUI is a less intrusive and expensive option, however, IUI treatment success rates are substantially lower than those of IVF.
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