Natural IVF cycle

Similar to normal IVF, natural cycle IVF uses very little medication to stimulate the female ovaries. Due to the fact that patients do not require daily gonadotropin injections, it is also known as "Drug-Free IVF."

Drugs are administered once a week or more during normal IVF to stimulate the ovaries and develop the eggs. In a natural cycle, the patient merely takes oral medications to speed the ovarian follicles' normal growth and get them ready to lay eggs. In natural IVF therapy, oral medicine is used to choose healthy, high-quality eggs for retrieval. The entire natural IVF process culminates with the administration of an injection to initiate ovulation in order to properly collect eggs once the medicinal procedure is finished.

Natural cycle IVF employs minimum stimulation IVF, also known as mini IVF, which gradually lowers the number of fertility medicines needed. Aiming for close to 2-4 eggs, natural IVF often uses modest dosages of hormones to boost egg production. For 10–12 days prior to egg retrieval, the natural cycle of IVF does not employ hormone injection to encourage multiple egg production while using the lowest amount of clomiphene citrate.

Who is Natural IVF best for?

Natural IVF can be the most useful for:

• women who are older than 35.
• Women who want to take fewer drugs when receiving reproductive therapy.
• hormone-stimulated women not able to generate egg follicles.
• women who have been recognized as being at risk for ovarian hyperstimulation syndrome (OHSS).
• women who have cancer or are receiving treatment.
• patients who don’t want to preserve their eggs or embryos.
• Patients who choose not to deal with extra eggs or embryos following IVF.
• women who have had more than two unsuccessful attempts at conception.
• those who have a history, familial difficulties, or genetic illnesses
• women who have had many miscarriages.

How is Natural IVF conducted?

The patient undergoing a natural IVF has to follow a four-step plan. Four steps of Natural IVF are: 

Step 1: Preparation for Natural IVF

Prior to starting the modified natural cycle IVF, a preliminary assessment is carried out to learn more about the reproductive health and conditions that may be preventing conception. The examination must be completed by the couple three to six months before the natural IVF cycle therapy begins.

The evaluation for women consists of:

• blood test to evaluate infertility
• transvaginal sonography (TVS)
• Examining the pelvis
• Hysterosalpingogram (HSG) (HSG)

The evaluation for males includes:

• Semen analysis
  Hemoglobin, VDRL, anti-HCV, and other blood tests are available.

Step 2: Hormonal Level Monitoring

To assess the results of the blood tests and the size of the follicles, women will have a vaginal ultrasound. Monitoring is carried out to confirm the proper course of treatment and the natural cycle IVF procedures that must be followed for the forthcoming treatment session.

Step 3: Sperm and Ovum Collection

The embryologist will collect the eggs while under heavy sedation. Following surgery, patients must remain in the hospital for additional observation. For males, however, sperm is harvested on-site to preserve the sperm sample's temperature.

Step 4: Preimplantation Genetic Screening (PGS)

It alludes to methods used to look at genetic and chromosomal anomalies. A review of Mitochondrial DNA testing and next-generation sequencing (NGS) is part of the PGS for the natural IVF procedure.

What are the Advantages of Natural IVF?

Natural IVF has many benefits and advantages as compared to other methods of IVF treatment. The patient needs no medication or less medication with less monitoring for a successful natural round of IVF. The couple does not have to wait longer between treatments because the ovaries are being treated naturally, so they may start another natural cycle IVF procedure right away. As a result, the overall success rates of natural IVF may be on par with or even greater than those of regular IVF. Additional benefits of natural IVF procedures include:

1. Conceiving with Own Egg

Natural cycle IVF offers the best chance for a woman who has blocked or damaged fallopian tubes to conceive with her own eggs. Instead of using laboratory procedures, natural alternatives to IVF (traditional) are used to support the natural IVF cycle with frozen embryos.

2. Patients With Low Ovarian Reserve

Success tales from natural IVF include those of elderly women with little ovarian reserve. Instead of emphasizing quantity, natural IVF treatments concentrate on egg quality.

3. Unexplained Infertility

1 in 6 couples experience reproductive issues, and occasionally, after comprehensive study, the cause of such infertility is still not known. The modified natural cycle IVF may be beneficial for these people without any help.

4. Male Infertility

Men with infertility issues have a better success percentage with IVF than with natural ways after undergoing the natural IVF cycle treatment. The hospitals that provide natural IVF have expert consultants who can appropriately counsel men who are having reproductive challenges and provide real ways to deal with infertility problems.

5. Premature Ovarian Failure

Women who have experienced menopause or early ovarian failure might benefit from a natural IVF cycle utilizing donated eggs. Additionally, natural IVF therapy can help females build a healthy family even after they reach the age of 40 or menopause due to the Natural cycle IVF success rates over 40.

6. PCOS

An irregular menstrual cycle is a frequent symptom of a hormonal imbalance. Patients with PCOS who choose not to undergo ovulation induction have shown success with IVF.

How Much Does Natural IVF Costs In Nepal?

The price of a natural cycle IVF relies on unique circumstances and customized plans, which will be further described by a natural fertility clinic's specialists. The finest natural IVF facility is Nepal IVF, which offers a variety of natural IVF treatment packages to assist patients in budgeting their medical expenses. Please get in touch with us if you'd like additional information.